Determining the incidence of familiality in ALS: A study of temporal trends in Ireland from 1994 to 2016.

Neurol Genet · 2018 · PMC5961194 · PMID 29845113

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an increasing trendno p-value reported

21 , 22 However, we have also identified an increasing trend in FALS ascertainment, ranging from 5.2% in 1994 to 19.1% in 2016, with over 50% of newly diagnosed FALS cases in 2016 coming from second generations within known FALS families.

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