A randomized placebo-controlled clinical trial of a multi-strain probiotic formulation (Bio-Kult®) in the management of diarrhea-predominant irritable bowel syndrome.

BMC Gastroenterol · 2018 · PMC5970461 · PMID 29801486

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highly significantno p-value reported

This is highlighted by a highly significant reduction in abdominal pain levels (primary outcome measure) during four months’ treatment and at follow-up (Fig. 2 ).

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