All of above mentioned interactions explain the highly significant inhibition of tubulin observed with compound 15k. 15k reverses metastasis in CRC cells The development of cancer metastasis is dependent on the migration and invasive properties of cancerous cells (van Zijl et al., 2011 ).
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Bax/Tubulin/Epithelial-Mesenchymal Pathways Determine the Efficacy of Silybin Analog HM015k in Colorectal Cancer Cell Growth and Metastasis.
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