TASK-3 Downregulation Triggers Cellular Senescence and Growth Inhibition in Breast Cancer Cell Lines.

We observed a highly significant decrease in the levels of the TASK-3 protein in MDA-MB-231 cells subjected to shK2P9A-, shK2P9B- and shK2P9C-mediated knockdown compared to the levels of the protein in cells that that were transduced with the vector control ( Figure 1 I).

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