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Determinants and Temporal Trends of Perfluoroalkyl Substances in Pregnant Women: The Hokkaido Study on Environment and Children's Health.

Int J Environ Res Public Health · 2018 · PMC5982028 · PMID 29758015

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a decreasing trendno p-value reported
In the present study, we set January 2006 as a cut-off time point and we observed that PFHxS concentration did not change before and after January 2006, whereas PFOS concentration showed a decreasing trend during both periods.

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an increasing trendno p-value reported
only reported that maternal PFOS levels were higher between 2000–2002 than between 2007–2008; maternal PFNA levels were lower between 2000–2002 than between 2007–2008, suggesting that there was a decreasing trend of PFOS and an increasing trend of PFNA [ 28 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.