Barely Significant
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Peritumoral endothelial indoleamine 2, 3-dioxygenase expression is an early independent marker of disease relapse in colorectal cancer and is influenced by DNA mismatch repair profile.

Oncotarget · 2018 · PMC5982767 · PMID 29861865

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hedged sentence
0.0040
closest p · 0.1× alpha
0.0040
boldest claim

The sentences

highly significantp = 0.004actually significant
Using this cut-off value, a highly significant prognostic role for CD8 on RFS was observed (Figure 2 , log-rank test, p = 0.004, cohort 2).

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