A highly significant inverse correlation of the intensity of luminescence with the frequency of T cells secreting IFN-γ in response to stimulation with peptides representing epitopes of PR aa 1-15 and 75-84 was observed starting from day 15 ( r > 0.5, p < 0.05; S3 Fig panels A, B).
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DNA immunization site determines the level of gene expression and the magnitude, but not the type of the induced immune response.
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