Moreover, the neuroligin-4 KO caused a reduction in mIPSC amplitude (to ∼65% of control values) that was highly significant because of the reproducibility of mIPSC amplitude measurements but did not alter the rise and decay times of mIPSCs ( Fig. 2, A and B ).
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Autism-associated neuroligin-4 mutation selectively impairs glycinergic synaptic transmission in mouse brainstem synapses.
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