Repurposing Dantrolene for Long-Term Combination Therapy to Potentiate Antisense-Mediated DMD Exon Skipping in the mdx Mouse.

Mol Ther Nucleic Acids · 2018 · PMC5992346 · PMID 29858053

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highly significantno p-value reported

Results indicate that e23AON has a highly significant positive treatment effect when considered across all e23AON concentrations combined relative to placebo-treated controls in both the quadriceps and diaphragm analyzed independently (p < 0.0001 for each, Figure S3 ).

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