Peptide inhibitors of the anaphase promoting-complex that cause sensitivity to microtubule poison.

PLoS One · 2018 · PMC5993284 · PMID 29883473

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partially significantno p-value reported

Tyc1-mut2 containing 5 amino acid residues TISLS changed to AAAAA in the C-terminus displayed a partially significant decrease in inhibition in both APC/C Cdc20 and a slight decrease in inhibiting APC/C Cdh1 ( Fig 11A and 11B ).

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