Clinical Significance of PTEN Deletion, Mutation, and Loss of PTEN Expression in De Novo Diffuse Large B-Cell Lymphoma.

Neoplasia · 2018 · PMC5994742 · PMID 29734016

Europe PMC DOI

hedged sentence

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

borderline significanceP = .06so close (0.05 < p ≤ 0.1)

Moreover, in p-AKT high GCB-DLBCL, loss of nuclear PTEN expression was associated with poorer PFS with borderline significance ( P = .06, Figure 2 B ), although it was associated with significantly lower mean levels of antiapoptotic Bcl-2 ( P = .0068) and MDM2 ( P = .0011) expression.

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