Investigating the viral ecology of global bee communities with high-throughput metagenomics.

Furthermore, our conservative bioinformatics filtering procedure (E-value < 1 × 10 −5 ) retained only a set of contigs with highly significant matches to viruses described in the NCBI nr database, thereby potentially removing sequences with homology to uncharacterized viral families (in only 3/37 samples, more contigs matched the viral databases than all potential sources of contamination and unmapped sequences combined).

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