Antiinflammatory Therapy in Clinical Care: The CANTOS Trial and Beyond.

Front Cardiovasc Med · 2018 · PMC5996084 · PMID 29922680

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highly significantno p-value reported

Further demonstrating this issue, random allocation to canakinumab as compared to placebo in CANTOS resulted in large and highly significant dose-dependent reductions in cancer fatality, incident lung cancer, and fatal lung cancer (Figure 4 ) ( 38 ).

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