near significancep = 0.06
Analysis of these data confirms that the tumor burden in the trastuzumab only group was significantly greater (p = 0.04) than that of the trastuzumab + FUS + MBs group (mean tumor volume = 25 ± 17 mm 3 vs 8 ± 5 mm 3 ), and near significance (p = 0.06) was observed between the trastuzumab + FUS + MBs group and the control group (24 ± 7 mm 3 ).