This reduction in the frequency of bursts in the dentate of knockout animals was concomitant with a highly significant drop in the mean firing rate and mean event rate in the CA3 region (Fig. 8 E – G ), consistent with the importance of the burst firing of granule cells for the effective triggering of their postsynaptic CA3 targets.
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The Low-Threshold Calcium Channel Cav3.2 Mediates Burst Firing of Mature Dentate Granule Cells.
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