13 Another trial from MD Anderson randomized 203 patients treated with IMRT to 75.6 Gy in 42 fractions versus 72 Gy in 30 fractions and found a nonsignificant trend toward inferior GI toxicity in the hypofractionated arm. 14 In addition, Fox Chase conducted a trial enrolling 303 patients and IMRT planning, randomizing patients between 76 Gy in 36 fractions versus 70.2 Gy in 26 fractions.
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Outcomes and toxicity from a prospective study of moderately hypofractionated radiation therapy for prostate cancer.
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