LRRK2 is a negative regulator of <i>Mycobacterium tuberculosis</i> phagosome maturation in macrophages.

EMBO J · 2018 · PMC6003659 · PMID 29789389

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highly significantno p-value reported

In agreement with these data, the phagosome proteome of HG‐10‐102‐01‐treated macrophages identified a highly significant decrease in total phosphatidylinositol‐3‐phosphate (PI3P)‐binding proteins upon LRRK2 kinase inhibition (Fig 4 B).

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