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Enhancing the dissolution of phenylbutazone using Syloid® based mesoporous silicas for oral equine applications.

J Pharm Anal · 2018 · PMC6004617 · PMID 29922487

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incredibly significantno p-value reported
Phenylbutazone is an excellent candidate for exploring the potential to enhance solubility through formulation with a dissolution-limiting low solubility yet incredibly significant usage within the equine community.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.