Barely Significant
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Purifying and positive selection in the evolution of stop codons.

Sci Rep · 2018 · PMC6006363 · PMID 29915293

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The sentences

highly significantp < 10 −324actually significant
Comparison of the genes with no change in the stop codon, with genes with a stop codon switch reveal a highly significant increase (p < 10 −324 ) in the frequency of substitutions immediately downstream of the stop codon in genes in the latter group, suggesting compensation between changes in the stop codon and in the immediate downstream region.

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