This regimen was based on a study carried out by the European Organization for the Research and Treatment of Cancer (EORTC) [ 27 , 28 ] consisting of 579 patients randomized to two arms, undergoing surgery plus either photon radiation alone or photon radiation in combination with TMZ, in order to demonstrate an increase in median overall survival of 2.5 months, which statistically was highly significant [ 28 ].
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A realistic appraisal of boron neutron capture therapy as a cancer treatment modality.
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