Human IgM antibody rHIgM22 promotes phagocytic clearance of myelin debris by microglia.

Sci Rep · 2018 · PMC6010437 · PMID 29925848

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a positive trendno p-value reported

While the patient cohort was not large enough to detect significant changes in clinical outcomes, Patient Global Impression of Change showed a positive trend in patients treated with rHIgM22.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.