Despite nearly 500 patients being included, only a positive trend for an overall survival advantage was observed from the use of adjuvant chemotherapy. 6 In the perioperative setting, the EORTC 40983 trial investigated the role of perioperative FOLFOX compared with metastasectomy alone.
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Role of chemotherapy in resectable liver metastases from colorectal cancer: food for thought from pooled evidence.
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