Interaction of Left Ventricular Size and Sex on Outcome of Cardiac Resynchronization Therapy Among Patients With a Narrow QRS Duration in the EchoCRT Trial.

In multivariable analysis, CRT‐ON increase d the proportion of patients reaching the primary end point in QRSd/LVEDV Q1–Q3 (31.7% in CRT‐ON [n=300] versus 24.8% in CRT‐OFF [n=290]; HR, 1.47; 95% CI, 1.07–2.02; P =0.016), but decreased it in QRSd/LVEDV Q4 (death/HF hospitalization, 20.9% in CRT‐ON [n=91] versus 28.3% in CRT‐OFF [n=106]; HR, 0.64; 95% CI, 0.34–1.24; borderline significant test for interaction P =0.046).

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