Importance of standardizing timing of hematocrit measurement when using cardiovascular magnetic resonance to calculate myocardial extracellular volume (ECV) based on pre- and post-contrast T1 mapping.

Even though they showed a significant correlation (r 2 = 0.51) between longitudinal relaxation rate of the blood and Hct measured from venous blood, there may be significant difference in actual ECV and synthetic ECV for individual patients, specifically pediatric patients and young adults [ 17 ], affecting the ability to detect relatively small differences in ECV between normal and diffuse disease or treated vs non-treated subjects.

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