Upregulation of Twist2 in Non-Muscle Invasive Urothelial Carcinoma of the Bladder Correlate with Response to Treatment and Progression.

Comparison between mean values of Twist2 expression in initial diagnosis of NMIBC and MIBC was highly significant (0.001), comparison between mean values of Twist2 expression in initial diagnosis of NMIBC and non-responders that had upstaged and upgraded in the follow-up was highly significant (0.001) ( Table 2 ) Univariable analysis of Twist2 expression in the initial diagnosis in relation to tumor grade and stage was highly significant (P 0.001); univariable analysis of Twist2 expression in relation to sex and gender was insignificant.

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