Global phosphoproteomics of CCR5-tropic HIV-1 signaling reveals reprogramming of cellular protein production pathways and identifies p70-S6K1 and MK2 as HIV-responsive kinases required for optimal infection of CD4+ T cells.

Retrovirology · 2018 · PMC6029029 · PMID 29970186

Europe PMC DOI

hedged sentence

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closest p · 0.0× alpha

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boldest claim

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highly significantp < 1.0 × 10 −15actually significant

Again, we found a highly significant overlap (Fig. 2 b), with 43.1% (401/931, p < 1.0 × 10 −15 ) of the HIV-responsive proteins identified here being part of the HHPID.

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