Isoquercetin and inulin synergistically affect metabolic signalling pathways Western blot analysis revealed a pronounced trend towards increased expression of the GLUT4 receptor in the liver and skeletal muscle of mice fed the HF diet supplemented with combination isoquercetin and inulin (Fig. 3A,B ), which was accompanied by a trend towards increased expression of the insulin receptor in the liver and skeletal muscle (Fig. 3C,D ).
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Isoquercetin and inulin synergistically modulate the gut microbiome to prevent development of the metabolic syndrome in mice fed a high fat diet.
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