Interaction between endothelial nitric oxide synthase rs1799983, cholesteryl ester-transfer protein rs708272 and angiopoietin-like protein 8 rs2278426 gene variants highly elevates the risk of type 2 diabetes mellitus and cardiovascular disease.

Cardiovasc Diabetol · 2018 · PMC6032560 · PMID 29973202

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highly significantno p-value reported

In a meta-analysis performed on 13,677 subjects, TaqIB variant exhibited a highly significant association with HDL-C levels and CAD, B2B2 individuals had significantly higher HDL-C levels than B1B1 individuals [ 14 ].

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