Barely Significant
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Linagliptin unmasks specific antioxidant pathways protective against albuminuria and kidney hypertrophy in a mouse model of diabetes.

PLoS One · 2018 · PMC6034861 · PMID 29979777

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highly significantno p-value reported
It is important to note that these mice are a C3H strain, not DBA/2J, as it is well known that there are highly significant mouse strain differences in susceptibility to the development of DKD and to the effectiveness of treatment.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.