The percentage changes observed with SI 800 mg/kg were comparatively greater than that of standard drugs D and M exhibiting its highly significant anti-rheumatoid activity ( Table 3 ). 4 Discussion Rheumatoid arthritis (RA) is a chronic multi system disease characterized by persistent inflammatory synovitis involving peripheral joints leading to progressive destruction of cartilages and bones resulting in functional impairment.
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Anti-rheumatoid activity of ethanolic extract of <i>Sesamum indicum</i> seed extract in Freund's complete adjuvant induced arthritis in Wistar albino rats.
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