Renal and Blood Pressure Response to a High-Salt Diet in Mice With Reduced Global Expression of the Glucocorticoid Receptor.

However, this normal physiological adaptation did not occur in GR βgeo/+ mice: Instead, neither Scnn1a mRNA abundance ( Figure 6C ) nor benzamil-sensitive sodium reabsorption significantly reduced with high salt ( Figure 6D ) and this differential response to dietary salt between genotypes was highly significant (Effect of genotype p < 0.001).

also in 132,142 other papers