Following the treatment with mApoE-PA-LIPs, cell capacitance and cell resting membrane potential did not change; however, the input resistance significantly increased by 17% in neurons incubated for 4 h with mApoE-PA-LIPs, even though an increasing trend was also present when the incubation lasted for just 1 h.
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Modulation of the intrinsic neuronal excitability by multifunctional liposomes tailored for the treatment of Alzheimer's disease.
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