Array comparative genomic hybridization identifies high level of PI3K/Akt/mTOR pathway alterations in anal cancer recurrences.

Long‐rank test demonstrated a significant correlation between poor OS and a large number of distinct CGH segments in recurrent tumors ( P = .024) (Figure 3 A), and a trend toward significance for a high fraction of the genome altered in treatment‐naive tumors ( P = .16) (Figure 3 B).

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