Hippocampal metabolites in asthma and their implications for cognitive function.

On the other hand, inhaled corticosteroid use (yes/no) was positively correlated with total Cr ( r = 0.70, p = 0.002) and demonstrated a positive trend with NAA ( r = 0.43, p = 0.082) and Glu ( r = 0.40, p = 0.113), indicating that those on inhaled corticosteroids, clinically recommended for long-term asthma control, had higher levels of Cr ( Table 4 ). 3.5.

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Differences between asthma and healthy groups Individuals with asthma had lower levels of both NAA, t (33) = −3.23, p = 0.003 ( d = 1.12) and Cr, t (33) = −3.31, p = 0.002 ( d = 1.15) compared to controls ( Table 2 ), and demonstrated a nonsignificant trend in that direction with Glu, U = 204.0, p = 0.096 ( d = 0.53) ( Fig. 2 ).

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