A complex of C9ORF72 and p62 uses arginine methylation to eliminate stress granules by autophagy.

Nat Commun · 2018 · PMC6052026 · PMID 30022074

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closest p · 0.0× alpha

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highly significantp = 1.57 × 10 −7actually significant

More broadly, mRNAs putatively mis-spliced in p62 −/− brains included a highly significant proportion of mRNAs (97 of 862, p = 1.57 × 10 −7 ) that bound to FUS and were mis-spliced in FUS-deficient brains 41 (Fig. 5m , Supplementary Fig. 5p ).

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