Neurofilament levels, disease activity and brain volume during follow-up in multiple sclerosis.

For the 12 CIS patients that converted to RRMS during the study, multiple regression modeling of time to conversion resulted in a highly significant model (adjusted R 2 0.81, p = 0.006) when including baseline CSF levels of CXCL1, CXCL10, CXCL13, and NFL, and number of T2 lesions at baseline).

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