Hepatitis C virus enters liver cells using the CD81 receptor complex proteins calpain-5 and CBLB.

PLoS Pathog · 2018 · PMC6053247 · PMID 30024968

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highly significantno p-value reported

As prey protein enrichment was limited in the co-IPs from HA-tagged CD81 expressing cells, we performed a second overlap analysis exclusively with the primary hepatocyte hits (>4-fold enrichment) and highly significant hepatoma cell hits (FDR = 0.004, s0 = 2) from cells with untagged CD81.

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