Although, early antiviral therapy can reverse liver fibrosis in patients with HBV and HCV infection (D'Ambrosio et al., 2012 ; Marcellin et al., 2013 ), for other causes of liver fibrosis and cirrhosis, there are still no effective anti‐fibrosis drugs applied to clinical treatment (Sun & Kisseleva, 2015 ), Therefore, developing anti‐liver fibrosis drugs is highly significant (Lee, Wallace, & Friedman, 2015 ).
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Ursolic acid ameliorates CCl4-induced liver fibrosis through the NOXs/ROS pathway.
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