highly significantP =0.023
The difference was highly significant for sorafenib vs. pazopanib in the incidence of all-grade rash (odds ratio [OR] 1.649, 95% CI 1.086–2.505, P =0.023), hand–foot syndrome (OR 3.096, 95% CI 1.271–7.544, P =0.009) and mucositis (OR 4.562, 95% CI 2.132–9.609, P <0.001).