Rad52-Rad51 association is essential to protect Rad51 filaments against Srs2, but facultative for filament formation.

Elife · 2018 · PMC6056232 · PMID 29985128

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barely significantno p-value reported

Therefore, the only possible explanation for the finding that these two Rad52 mutants show only a slight decrease in viability after HO cut (not statistically significant for the rad52-P381S and barely significant for the rad52-Y376A mutant) is that Rad51 filaments are formed at the DSB site, which is observed at another locus in our ChIP experiments.

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