Those methods were reported to be strikingly successful, and precisions above 90% were achieved by the best predictors in more than half the targets in CASP12, a result considered to be a highly significant improvement compared with the results obtained during CASP11 108 .
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Combined approaches from physics, statistics, and computer science for <i>ab initio</i> protein structure prediction: <i>ex unitate vires</i> (unity is strength)?
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We also note an interesting trend within the field of MD simulations in terms of methods development.