Biomarker repurposing: Therapeutic drug monitoring of serum theophylline offers a potential diagnostic biomarker of Parkinson's disease.

PLoS One · 2018 · PMC6059449 · PMID 30044870

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failed to reach significanceno p-value reported

This may have weakened the statistical power, possibly leading to the result that the difference in theophylline levels between PD groups with and without motor complications failed to reach significance [ 8 ].

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