Barely Significant
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Biophysical clocks face a trade-off between internal and external noise resistance.

Elife · 2018 · PMC6059770 · PMID 29988019

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an overall trendno p-value reported
Further, there is an overall trend in Prochlorococcus towards reduced genome size and cell size which likely imply increased internal noise.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.