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MD1003 (High-Dose Pharmaceutical-Grade Biotin) for the Treatment of Chronic Visual Loss Related to Optic Neuritis in Multiple Sclerosis: A Randomized, Double-Blind, Placebo-Controlled Study.

CNS Drugs · 2018 · PMC6061426 · PMID 29808469

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an interesting trendno p-value reported
An interesting trend favoring MD1003 was observed in the subgroup of patients with PON.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.