The block of highly significant associations discovered here could theoretically impact any of the genes within the collectin locus, as DNA kilobases to megabases upstream of genes can have a regulatory impact through enhancer, silencer, insulator, or locus control region elements (Maston et al. 2006 ) that are difficult to predict, and for which the bovine genome lacks annotation.
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Identification of polymorphisms in the bovine collagenous lectins and their association with infectious diseases in cattle.
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