Molecular Profiling of Follicular Variant of Papillary Thyroid Cancer Reveals Low-Risk Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features: A Paradigm Shift to Reduce Aggressive Treatment of Indolent Tumors.

Clinicopathological features and molecular profile of invasive EFVPTC and NIFTP were analyzed in different series of patients, but none of those studies included the infiltrative/diffusing FVPTC.[ 1 , 10 , 11 , 25 , 26 , 27 ] On clinicopathological correlation analysis, we found the rate of lymph node metastasis in infiltrative subtype of FVPTC is close to the rates of cPTCs which was highly significant in comparison with invasive EFVPTC and NIFTP ( P = 0.0004) [ Table 1 ].

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