borderline significanceP = 0.0501
Univariate analysis identified that an age > 40 years, female sex, HBV genotype C, baseline HBsAg < 3.0 log 10 IU/mL, HBV DNA < 6 log 10 IU/mL, ALT < 5× ULN, platelet < 150 × 10 3 /uL were significantly associated with METAVIR fibrosis stages 3 and 4, while CLEC18 showed borderline significance ( P = 0.0501).