Barely Significant
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GC content elevates mutation and recombination rates in the yeast <i>Saccharomyces cerevisiae</i>.

Proc Natl Acad Sci U S A · 2018 · PMC6064992 · PMID 29987035

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The sentences

highly significantP < 0.0001actually significant
The elevated number of large indels for URA3-GC relative to URA3-WT is highly significant ( P < 0.0001 by Fisher exact test).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.