Inhibition of Nox4-dependent ROS signaling attenuates prostate fibroblast activation and abrogates stromal-mediated protumorigenic interactions.

GKT137831 had no significant effect on Nox1/Nox4 mRNA levels in basal or TGFβ1‐treated prostate fibroblasts although we noted a nonsignificant trend toward increased Nox4 protein levels (Fig. 4 ab and Supporting Information, Figs.

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