Barely Significant
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Reimmunization increases contraceptive effectiveness of gonadotropin-releasing hormone vaccine (GonaCon-Equine) in free-ranging horses (Equus caballus): Limitations and side effects.

PLoS One · 2018 · PMC6067756 · PMID 30063758

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highly significantno p-value reported
Unlike results from the single vaccination trial, we observed, not only highly significant reduction in foaling proportions between treated and control mares following reimmunization but also a remarkably effective contraceptive response.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.